1. Check to make sure you are all set to take on a Big Daddy. Do you have any of the things listed in the "Things You'll Need" section? Do you have...

2. Know your environment. Have you hacked any turrets that you can use? Have disabled all those annoying security cameras? Have you gotten rid of o...

3. Battle with the tactics you can afford. Depending on what types of ammunition you can afford to buy or make, you should try different, and often...

4. If you have explosive shotgun shells, use 'em. They are usually over-kill against any lesser enemies, even Spider Splicers, so they are being pu...

5. If you have electric shotgun shells, alternate between using the electric shells and other weapons. The electric shells zap the Big Daddy into p...

6. If you have some Proximity Mines and the Telekinesis plasmid, you can take out the monster in one shot. Though using your Proximity Mines may se...

7. If you (like most conservative players) almost never use your RPGs (Rocket propelled grenades) or fragmentation grenades, then here's where your...

8. If you have the 'Hypnotize Big Daddy' plasmids, you can pull off an entertaining end to multiple Big Daddies. Once you have used the plasmid on...

9. If you have finally gotten the crossbow, you can set up a trap for Big Daddies. Trap bolts are powerful, but not so practical against normal foe...

10. Scavenge what you can. Big Daddies offer a large sum of money, as well as many inventing items. Using the 'Scrounger' tonic (found by researchi...