According to ACOG, your chance of getting pregnant naturally after 45 is unlikely. That's not to say it's impossible, but assisted reproductive technologies (ART) are almost always necessary, with IVF being the most common.

By age 45, the American College of Obstetricians and Gynecologists says that getting pregnant naturally is unlikely for most women. After age 45, you will probably need to use assisted reproductive technology, such as in-vitro fertilization (IVF), to get pregnant.