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- Mast cell activation syndrome (MCAS) is one of a group of diseases known as mastocytoses. It is a condition caused by mast cells being too easily stimulated, which makes them release certain substances and degranulate. In other words, mast cells become ultra-reactive to stimuli, which is considered abnormal.www.carenity.co.uk/condition-information/magazine/news/what-is-mast-cell-acti…
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