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- While pregnancy after 45 is possible, it is considered a high-risk pregnancy. This is because fertility decreases with increasing age, and concerns such as miscarriages, gestational diabetes, and preterm birth become common. There is also an increased risk of having a baby with chromosomal abnormalities such as Down syndrome.www.momjunction.com/articles/pregnancy-at-age-45-and-after-45_00395303/
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